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Pharmacokinetic Differences Corroborate Observed Low Tacrolimus Dosage in Native American Renal Transplant Patients

We have observed in clinical practice that Native Americans require lower dosages of tacrolimus to attain similar target blood trough levels compared to whites after renal transplant. Because there are no pharmacokinetic studies of tacrolimus in this ethnic group, we investigated whether this clinic...

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Main Authors: Grover, Anita, Frassetto, Lynda A., Benet, Leslie Z., Chakkera, Harini A.
Formáid: Artigo
Teanga:Inglês
Foilsithe: The American Society for Pharmacology and Experimental Therapeutics 2011
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3198899/
https://ncbi.nlm.nih.gov/pubmed/21849516
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/dmd.111.041350
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