Hydroxyfasudil-Mediated Inhibition of ROCK1 and ROCK2 Improves Kidney Function in Rat Renal Acute Ischemia-Reperfusion Injury

Renal ischemia-reperfusion (IR) injury (IRI) is a common and important trigger of acute renal injury (AKI). It is inevitably linked to transplantation. Involving both, the innate and the adaptive immune response, IRI causes subsequent sterile inflammation. Attraction to and transmigration of immune...

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Главные авторы: Kentrup, Dominik, Reuter, Stefan, Schnöckel, Uta, Grabner, Alexander, Edemir, Bayram, Pavenstädt, Hermann, Schober, Otmar, Schäfers, Michael, Schlatter, Eberhard, Büssemaker, Eckhart
Формат: Artigo
Язык:Inglês
Опубликовано: Public Library of Science 2011
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Research Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3198766/
https://ncbi.nlm.nih.gov/pubmed/22031832
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0026419
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