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Specific transcription of mouse ribosomal DNA in a cell-free system that mimics control in vivo.

Cloned ribosomal DNA (rDNA) from mouse, which contains the initiation site of 45S pre-rRNA transcription and 5' flanking sequences, has been used as the template in an in vitro transcription system. In the presence of extracts from rapidly growing Ehrlich ascites cells, RNA polymerase I initiat...

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Bibliographic Details
Published in:Proc Natl Acad Sci U S A
Main Author: Grummt, I
Format: Artigo
Language:Inglês
Published: National Academy of Sciences 1981
Subjects:
Online Access:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC319875/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6262766/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.78.2.727
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