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GABA Coordinates with Insulin in Regulating Secretory Function in Pancreatic INS-1 β-Cells
Pancreatic islet β-cells produce large amounts of γ-aminobutyric acid (GABA), which is co-released with insulin. GABA inhibits glucagon secretion by hyperpolarizing α-cells via type-A GABA receptors (GABA(A)Rs). We and others recently reported that islet β-cells also express GABA(A)Rs and that activ...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Public Library of Science
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3198728/ https://ncbi.nlm.nih.gov/pubmed/22031825 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0026225 |
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