Monocyte Chemoattractant Protein-1-Deficiency Impairs the Expression of IL-6, IL-1β and G-CSF after Transient Focal Ischemia in Mice

Monocyte chemoattractant protein-1 (MCP-1), a chemokine secreted by neurons and astrocytes following stroke is known to aggravate ischemia-related damage. Previous studies revealed that MCP-1-deficient mice develop smaller infarcts and have an improved neurological outcome, whereas mice overexpressi...

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Главные авторы: Strecker, Jan-Kolja, Minnerup, Jens, Gess, Burkhard, Ringelstein, E. Bernd, Schäbitz, Wolf-Rüdiger, Schilling, Matthias
Формат: Artigo
Язык:Inglês
Опубликовано: Public Library of Science 2011
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Research Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3198727/
https://ncbi.nlm.nih.gov/pubmed/22031820
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0025863
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