Increased intestinal permeability and tight junction disruption by altered expression and localization of occludin in a murine graft versus host disease model

BACKGROUND: Hematopoietic stem cell transplantation is increasingly performed for hematologic diseases. As a major side effect, acute graft versus host disease (GvHD) with serious gastrointestinal symptoms including diarrhea, gastrointestinal bleeding and high mortality can be observed. Because surv...

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Main Authors: Noth, Rainer, Lange-Grumfeld, Julia, Stüber, Eckhard, Kruse, Marie-Luise, Ellrichmann, Mark, Häsler, Robert, Hampe, Jochen, Bewig, Burkhard, Rosenstiel, Philip, Schreiber, Stefan, Arlt, Alexander
Format: Artigo
Jezik:Inglês
Izdano: BioMed Central 2011
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3198696/
https://ncbi.nlm.nih.gov/pubmed/21977944
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-230X-11-109
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