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Hypoxic pulmonary hypertension in mice with constitutively active platelet-derived growth factor receptor-β
Platelet-derived growth factor (PDGF) has been implicated in the pathobiology of vascular remodeling. The multikinase inhibitor imatinib that targets PDGF receptor (PDGFR), c-kit and Abl kinases, shows therapeutic efficacy against experimental pulmonary hypertension (PH); however, the role of PDGFR-...
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| 主要な著者: | , , , , , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Medknow Publications
2011
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3198653/ https://ncbi.nlm.nih.gov/pubmed/22034611 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4103/2045-8932.83448 |
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