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RMRP Is a Non-Coding RNA Essential for Early Murine Development

RMRP is a non-coding RNA that is ubiquitously expressed in both humans and mice. RMRP mutations that lead to decreased RMRP levels are found in the pleiotropic syndrome Cartilage Hair Hypoplasia. To assess the effects of deleting RMRP, we engineered a targeting vector that contains loxP sequences fl...

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Detalhes bibliográficos
Main Authors: Rosenbluh, Joseph, Nijhawan, Deepak, Chen, Zhao, Wong, Kwok-Kin, Masutomi, Kenkichi, Hahn, William C.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2011
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3198473/
https://ncbi.nlm.nih.gov/pubmed/22039455
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0026270
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