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Overexpression of CD36 and Acyl-CoA Synthetases FATP2, FATP4 and ACSL1 Increases Fatty Acid Uptake in Human Hepatoma Cells

Background: Understanding the mechanisms of long chain fatty acid (LCFA) uptake in hepatic cells is of high medical importance to treat and to prevent fatty liver disease (FLD). ACSs (Acyl-CoA synthetases) are a family of enzymes that catalyze the esterification of fatty acids (FA) with CoA. Recent...

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Main Authors: Krammer, Julia, Digel, Margarete, Ehehalt, Friedrich, Stremmel, Wolfgang, Füllekrug, Joachim, Ehehalt, Robert
Formato: Artigo
Idioma:Inglês
Publicado: Ivyspring International Publisher 2011
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3198256/
https://ncbi.nlm.nih.gov/pubmed/22022213
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