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The effects of magnesium sulfate infiltration on perioperative opioid consumption and opioid-induced hyperalgesia in patients undergoing robot-assisted laparoscopic prostatectomy with remifentanil-based anesthesia

BACKGROUND: Opioids not only exert an antinociceptive effect, but also modulate central N-methyl-D-aspartate (NMDA) receptors, resulting in hyperalgesia and acute opioid tolerance. This study was aimed to investigate the effect of the NMDA receptor antagonist, magnesium in preventing remifentanil-in...

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Bibliografski detalji
Glavni autori: Lee, Cheol, Song, Yoon-Kang, Jeong, Hyun-Myun, Park, Seong-Nam
Format: Artigo
Jezik:Inglês
Izdano: The Korean Society of Anesthesiologists 2011
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3198187/
https://ncbi.nlm.nih.gov/pubmed/22025948
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4097/kjae.2011.61.3.244
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