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The tRNA(Met) 4435A>G mutation in the mitochondrial haplogroup G2a1 is responsible for maternally inherited hypertension in a Chinese pedigree

Mutations in mitochondrial DNA (mtDNA) have been associated with hypertension in several pedigrees with maternal inheritance. However, the pathophysiology of maternally inherited hypertension remains poorly understood. We reported here clinical, genetic evaluations and molecular analysis of mtDNA in...

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Autori principali: Lu, Zhongqiu, Chen, Hong, Meng, Yanzi, Wang, Yan, Xue, Ling, Zhi, Shaoce, Qiu, Qiaomeng, Yang, Li, Mo, Jun Qin, Guan, Min-Xin
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group 2011
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3198143/
https://ncbi.nlm.nih.gov/pubmed/21694735
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ejhg.2011.111
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