Specific Control of Pancreatic Endocrine β- and δ-Cell Mass by Class IIa Histone Deacetylases HDAC4, HDAC5, and HDAC9

OBJECTIVE: Class IIa histone deacetylases (HDACs) belong to a large family of enzymes involved in protein deacetylation and play a role in regulating gene expression and cell differentiation. Previously, we showed that HDAC inhibitors modify the timing and determination of pancreatic cell fate. The...

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Hlavní autoři: Lenoir, Olivia, Flosseau, Kathleen, Ma, Feng Xia, Blondeau, Bertrand, Mai, Antonello, Bassel-Duby, Rhonda, Ravassard, Philippe, Olson, Eric N., Haumaitre, Cécile, Scharfmann, Raphaël
Médium: Artigo
Jazyk:Inglês
Vydáno: American Diabetes Association 2011
Témata:
Islet Studies
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3198089/
https://ncbi.nlm.nih.gov/pubmed/21953612
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/db11-0440
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