Expansion of Th17 Cells and Functional Defects in T Regulatory Cells Are Key Features of the Pancreatic Lymph Nodes in Patients With Type 1 Diabetes

OBJECTIVE: Autoimmune diseases, including type 1 diabetes, are thought to have a Th17-cell bias and/or a T-regulatory cell (Treg) defect. Understanding whether this is a hallmark of patients with type 1 diabetes is a crucial question that is still unsolved, largely due to the difficulties of accessi...

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Detalhes bibliográficos
Main Authors: Ferraro, Alessandra, Socci, Carlo, Stabilini, Angela, Valle, Andrea, Monti, Paolo, Piemonti, Lorenzo, Nano, Rita, Olek, Sven, Maffi, Paola, Scavini, Marina, Secchi, Antonio, Staudacher, Carlo, Bonifacio, Ezio, Battaglia, Manuela
Formato: Artigo
Idioma:Inglês
Publicado em: American Diabetes Association 2011
Assuntos:
Immunology and Transplantation
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3198077/
https://ncbi.nlm.nih.gov/pubmed/21896932
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/db11-0090
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