miR-146a–Mediated Extracellular Matrix Protein Production in Chronic Diabetes Complications

OBJECTIVE: microRNAs (miRNAs), through transcriptional regulation, modulate several cellular processes. In diabetes, increased extracellular matrix protein fibronectin (FN) production is known to occur through histone acetylator p300. Here, we investigated the role of miR-146a, an FN-targeting miRNA...

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Detalhes bibliográficos
Main Authors: Feng, Biao, Chen, Shali, McArthur, Kara, Wu, Yuexiu, Sen, Subhrojit, Ding, Qingming, Feldman, Ross D., Chakrabarti, Subrata
Formato: Artigo
Idioma:Inglês
Publicado em: American Diabetes Association 2011
Assuntos:
Complications
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3198068/
https://ncbi.nlm.nih.gov/pubmed/21885871
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/db11-0478
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