Diffusional mechanisms augment the fluorine magnetic resonance relaxation in paramagnetic perfluorocarbon nanoparticles that provides a “relaxation switch” for detecting cellular endosomal activation

PURPOSE: To develop a physical model for the (19)F relaxation enhancement in paramagnetic perfluorocarbon nanoparticles (PFC NP) and demonstrate its application in monitoring cellular endosomal functionality through a “(19)F relaxation switch” phenomenon. MATERIALS AND METHODS: An explicit expressio...

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Bibliographic Details
Main Authors: Hu, Lingzhi, Zhang, Lei, Chen, Junjie, Lanza, Gregory M., Wickline, Samuel A.
Format: Artigo
Language:Inglês
Published: 2011
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3197905/
https://ncbi.nlm.nih.gov/pubmed/21761488
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jmri.22656
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