Suppression of Amygdalar Endocannabinoid Signaling by Stress Contributes to Activation of the Hypothalamic-Pituitary-Adrenal Axis

Endocannabinoids inhibit hypothalamic-pituitary-adrenal (HPA) axis activity; however, the neural substrates and pathways subserving this effect are not well characterized. The amygdala is a forebrain structure that provides excitatory drive to the HPA axis under conditions of stress. The aim of this...

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Autors principals: Hill, Matthew N., McLaughlin, Ryan J., Morrish, Anna C., Viau, Victor, Floresco, Stan B., Hillard, Cecilia J., Gorzalka, Boris B.
Format: Artigo
Idioma:Inglês
Publicat: 2009
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3197779/
https://ncbi.nlm.nih.gov/pubmed/19710634
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/npp.2009.114
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