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Regio- and Stereo-selective Syntheses of the Natural Product CCR5 Antagonist Anibamine and its Three Olefin Isomers

The syntheses of the natural product anibamine and its three olefin isomers have been achieved concisely and efficiently via highly regio- and stereo-selective reactions. The crucial steps included a regio-selective palladium-catalyzed alkynylation by Sonogashira coupling and a stereo-selective Suzu...

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Detalhes bibliográficos
Main Authors: Zhang, Feng, Zaidi, Saheem, Haney, Kendra M., Kellogg, Glen E., Zhang, Yan
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3197777/
https://ncbi.nlm.nih.gov/pubmed/21875065
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jo2013669
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