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Absence of phagocyte NADPH oxidase 2 leads to severe inflammatory response in lungs of mice infected with Coccidioides

Production of reactive oxygen species (ROS) resulting from phagocytic NADPH oxidase (NOX2) activity has been reported to contribute to host defense against numerous microbial pathogens. In this study we explored the role of NOX2 production in experimental coccidioidomycosis, a human respiratory dise...

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Bibliographische Detailangaben
Hauptverfasser: Gonzalez, Angel, Hung, Chiung-Yu, Cole, Garry T.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2011
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3197751/
https://ncbi.nlm.nih.gov/pubmed/21896326
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.micpath.2011.08.003
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