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Polymerase Chaperoning and Multiple ATPase Sites Enable the E. coli DNA Polymerase III Holoenzyme to Rapidly Form Initiation Complexes

Cellular replicases include three subassemblies: a DNA polymerase, a sliding clamp processivity factor, and a clamp loader complex. The E. coli clamp loader is the DnaX complex (DnaX(3)δδ'χψ), where DnaX occurs either as τ or as the shorter γ that arises by translational frameshifting. Complexe...

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Detalhes bibliográficos
Main Authors: Downey, Christopher D., Crooke, Elliott, McHenry, Charles S.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3197712/
https://ncbi.nlm.nih.gov/pubmed/21820444
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2011.07.051
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