Metabolic conversion of dibenz[a,h]anthracene (+/-)trans-1,2-dihydrodiol and chrysene (+/-)trans-3,4-dihydrodiol to vicinal dihydrodiol epoxides.

The hydroxyl groups of dibenz[a,h]anthracene trans-1,2-dihydrodiol and chrysene trans-3,4-dihydrodiol are known to be predominantly in quasi-axial conformations. These dihydrodiols were metabolized by liver microsomes from 3-methylcholanthrene-pretreated rats to form 1,2,3,4-tetrahydrotetrols as the...

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Vydáno v:	Proc Natl Acad Sci U S A
Hlavní autoři:	Chou, M W, Fu, P P, Yang, S K
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	National Academy of Sciences 1981
Témata:	Research Article
On-line přístup:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC319771/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6945583/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.78.7.4270
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