3-Hydroxy Kynurenine Treatment Controls T. cruzi Replication and the Inflammatory Pathology Preventing the Clinical Symptoms of Chronic Chagas Disease

BACKGROUND: 3-Hydroxy Kynurenine (3-HK) administration during the acute phase of Trypanosoma. cruzi infection decreases the parasitemia of lethally infected mice and improves their survival. However, due to the fact that the treatment with 3-HK is unable to eradicate the parasite, together with the...

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Main Authors: Knubel, Carolina P., Martínez, Fernando F., Acosta Rodríguez, Eva V., Altamirano, Andrés, Rivarola, Héctor W., Diaz Luján, Cintia, Fretes, Ricardo E., Cervi, Laura, Motrán, Claudia C.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2011
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3197528/
https://ncbi.nlm.nih.gov/pubmed/22028903
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0026550
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