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Chicken interferon alpha pretreatment reduces virus replication of pandemic H1N1 and H5N9 avian influenza viruses in lung cell cultures from different avian species

BACKGROUND: Type I interferons, including interferon alpha (IFN-α), represent one of the first lines of innate immune defense against influenza virus infection. Following natural infection of chickens with avian influenza virus (AIV), transcription of IFN-α is quickly up regulated along with multipl...

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Main Authors: Jiang, Haijun, Yang, Hanchun, Kapczynski, Darrell R
Formato: Artigo
Idioma:Inglês
Publicado: BioMed Central 2011
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3197513/
https://ncbi.nlm.nih.gov/pubmed/21939525
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1743-422X-8-447
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