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Microarray profiling reveals the integrated stress response is activated by halofuginone in mammary epithelial cells
BACKGROUND: The small molecule Halofuginone (HF) is a potent regulator of extracellular matrix (ECM ) gene expression and is unique in its therapeutic potential. While the basis for HF effects is unknown, inhibition of TGFβ signaling and activation of the amino acid restriction response (AAR) have b...
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| Main Authors: | , , , , |
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| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
BioMed Central
2011
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3197508/ https://ncbi.nlm.nih.gov/pubmed/21974968 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1756-0500-4-381 |
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