Cardiac pressure overload hypertrophy is differentially regulated by β-adrenergic receptor subtypes

In isolated myocytes, hypertrophy induced by norepinephrine is mediated via α(1)-adrenergic receptors (ARs) and not β-ARs. However, mice with deletions of both major cardiac α(1)-ARs still develop hypertrophy in response to pressure overload. Our purpose was to better define the role of β-AR subtype...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Zhao, Mingming, Fajardo, Giovanni, Urashima, Takashi, Spin, Joshua M., Poorfarahani, Sara, Rajagopalan, Viswanathan, Huynh, Diem, Connolly, Andrew, Quertermous, Thomas, Bernstein, Daniel
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: American Physiological Society 2011
Gaiak:
Signaling and Stress Response
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3197363/
https://ncbi.nlm.nih.gov/pubmed/21705675
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpheart.00453.2010
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