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Cardiac pressure overload hypertrophy is differentially regulated by β-adrenergic receptor subtypes
In isolated myocytes, hypertrophy induced by norepinephrine is mediated via α(1)-adrenergic receptors (ARs) and not β-ARs. However, mice with deletions of both major cardiac α(1)-ARs still develop hypertrophy in response to pressure overload. Our purpose was to better define the role of β-AR subtype...
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| Main Authors: | , , , , , , , , , |
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| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
American Physiological Society
2011
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3197363/ https://ncbi.nlm.nih.gov/pubmed/21705675 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpheart.00453.2010 |
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