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The PGC-1α-related coactivator promotes mitochondrial and myogenic adaptations in C2C12 myotubes

The transcriptional coactivator PGC-1α is a potent regulator of skeletal muscle metabolism. Less is known about the structurally similar PGC-1α-related coactivator (PRC) that is enriched in myoblasts and adult skeletal muscle. The present study was designed to determine the effect of PRC on the meta...

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Detalhes bibliográficos
Main Authors: Philp, Andrew, Belew, Micah Y., Evans, Ashleigh, Pham, Don, Sivia, Itwinder, Chen, Ai, Schenk, Simon, Baar, Keith
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2011
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3197342/
https://ncbi.nlm.nih.gov/pubmed/21795630
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpregu.00232.2011
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