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Administration of 3-methylcholanthrene to rats increases the specific hybridizable mRNA coding for cytochrome P-450c.

Poly(A)+-RNA obtained from the livers of 3-methylcholanthrene (3MC)-treated rats was translated into cytochrome P-450c in a cell-free reticulocyte system. In this translational system, no precursor cytochrome P-450c was observed. The mRNA responsible for the synthesis of this cytochrome was isolated...

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Udgivet i:Proc Natl Acad Sci U S A
Principais autores: Bresnick, E, Brosseau, M, Levin, W, Reik, L, Ryan, D E, Thomas, P E
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 1981
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC319730/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6945571/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.78.7.4083
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