Pharmacologic Antagonism of Ghrelin Receptors Attenuates Development of Nicotine Induced Locomotor Sensitization in Rats

AIMS: Ghrelin (GHR) is an orexigenic gut peptide that interacts with ghrelin receptors (GHR-Rs) to modulate brain reinforcement circuits. Systemic GHR infusions augment cocaine stimulated locomotion and conditioned place preference (CPP) in rats, whereas genetic or pharmacological ablation of GHR-Rs...

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Detalhes bibliográficos
Main Authors: Wellman, Paul J., Clifford, P. Shane, Rodriguez, Juan, Hughes, Samuel, Eitan, Shoshana, Brunel, Luc, Fehrentz, Jean-Alain, Martinez, Jean
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3197247/
https://ncbi.nlm.nih.gov/pubmed/21903141
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.regpep.2011.08.014
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