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Chronic Morphine Alters the Presynaptic Protein Profile: Identification of Novel Molecular Targets Using Proteomics and Network Analysis

Opiates produce significant and persistent changes in synaptic transmission; knowledge of the proteins involved in these changes may help to understand the molecular mechanisms underlying opiate dependence. Using an integrated quantitative proteomics and systems biology approach, we explored changes...

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Main Authors: Abul-Husn, Noura S., Annangudi, Suresh P., Ma'ayan, Avi, Ramos-Ortolaza, Dinah L., Stockton, Steven D., Gomes, Ivone, Sweedler, Jonathan V., Devi, Lakshmi A.
格式: Artigo
語言:Inglês
出版: Public Library of Science 2011
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3197197/
https://ncbi.nlm.nih.gov/pubmed/22043286
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0025535
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