Solubilization of human platelet alpha-adrenergic receptors: evidence that agonist occupancy of the receptor stabilizes receptor--effector interactions.

The alpha-adrenergic receptors of human platelet membranes can be directly identified by both a radiolabeled agonist, [3H]epinephrine, and a radiolabeled antagonist, [3H]yohimbine. Digitonin solubilizes a binding component from the membrane that is indistinguishable from the alpha-receptor identifie...

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Sparad:
Bibliografiska uppgifter
Huvudupphovsmän: Smith, S K, Limbird, L E
Materialtyp: Artigo
Språk:Inglês
Publicerad: 1981
Ämnen:
Research Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC319718/
https://ncbi.nlm.nih.gov/pubmed/6270654
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