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Impaired ATP release from red blood cells promotes their adhesion to endothelial cells: A mechanism of hypoxemia after transfusion

OBJECTIVE: Transfusion of red blood cells (RBCs) has been linked to disappointing clinical outcomes in the critically ill, but specific mechanisms of organ dysfunction after transfusion remain poorly understood. We tested the hypothesis that RBC storage impairs the ability of RBCs to release ATP and...

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Detalhes bibliográficos
Main Authors: Zhu, Hongmei, Zennadi, Rahima, Xu, Bruce X., Eu, Jerry P., Torok, Jordan A., Telen, Marilyn J., McMahon, Timothy J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3196852/
https://ncbi.nlm.nih.gov/pubmed/21765360
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/CCM.0b013e318225754f
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