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Telomeres avoid end detection by severing the checkpoint signal transduction pathway

Telomeres protect the normal ends of chromosomes from being recognized as deleterious DNA double-strand breaks. Recent studies have uncovered an apparent paradox: although DNA repair is prevented, several proteins involved in DNA damage processing and checkpoint responses are recruited to telomeres...

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Bibliografski detalji
Glavni autori: Carneiro, Tiago, Khair, Lyne, Reis, Clara C., Borges, Vanessa, Moser, Bettina A., Nakamura, Toru M., Ferreira, Miguel Godinho
Format: Artigo
Jezik:Inglês
Izdano: 2010
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3196630/
https://ncbi.nlm.nih.gov/pubmed/20829797
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature09353
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