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Probing the Functional Mechanism of Escherichia coli GroEL Using Circular Permutation

BACKGROUND: The Escherichia coli chaperonin GroEL subunit consists of three domains linked via two hinge regions, and each domain is responsible for a specific role in the functional mechanism. Here, we have used circular permutation to study the structural and functional characteristics of the GroE...

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Detalhes bibliográficos
Main Authors: Mizobata, Tomohiro, Uemura, Tatsuya, Isaji, Kazuhiro, Hirayama, Takuma, Hongo, Kunihiro, Kawata, Yasushi
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3196576/
https://ncbi.nlm.nih.gov/pubmed/22028884
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0026462
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