Pigment Epithelium-Derived Factor (PEDF) Interacts with Transportin SR2, and Active Nuclear Import Is Facilitated by a Novel Nuclear Localization Motif

PEDF (Pigment epithelium-derived factor) is a non-inhibitory member of the serpin gene family (serpinF1) that displays neurotrophic and anti-angiogenic properties. PEDF contains a secretion signal sequence, but although originally regarded as a secreted extracellular protein, endogenous PEDF is foun...

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Detalhes bibliográficos
Main Authors: Anguissola, Sergio, McCormack, William J., Morrin, Michelle A., Higgins, Wayne J., Fox, Denise M., Worrall, D. Margaret
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2011
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3196545/
https://ncbi.nlm.nih.gov/pubmed/22028839
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0026234
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