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Cumulative Number of Cell Divisions as a Meaningful Timescale for Adaptive Laboratory Evolution of Escherichia coli

Adaptive laboratory evolution (ALE) under controlled conditions has become a valuable approach for the study of the genetic and biochemical basis for microbial adaptation under a given selection pressure. Conventionally, the timescale in ALE experiments has been set in terms of number of generations...

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Autori principali: Lee, Dae-Hee, Feist, Adam M., Barrett, Christian L., Palsson, Bernhard Ø.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2011
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3196513/
https://ncbi.nlm.nih.gov/pubmed/22028828
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0026172
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