Involvement of Endoplasmic Reticulum Stress in Inflammatory Bowel Disease: A Different Implication for Colonic and Ileal Disease?

BACKGROUND: Endoplasmic reticulum (ER) stress has been suggested to play a role in inflammatory bowel disease (IBD). The three branches (ATF6, IRE1 and PERK) of the unfolded protein response (UPR) have different roles and are not necessarily activated simultaneously. METHODOLOGY/PRINCIPAL FINDINGS:...

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Detalhes bibliográficos
Main Authors: Bogaert, Sara, De Vos, Martine, Olievier, Kim, Peeters, Harald, Elewaut, Dirk, Lambrecht, Bart, Pouliot, Philippe, Laukens, Debby
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2011
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3196494/
https://ncbi.nlm.nih.gov/pubmed/22028783
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0025589
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