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Separable Determinants of Subcellular Localization and Interaction Account for the Inability of Group O HIV-1 Vpu To Counteract Tetherin

Tetherin (BST-2/CD317) is thought to restrict retroviral particle release by cross-linking nascent viral and cellular membranes. Unlike the Vpu proteins encoded by human immunodeficiency virus type 1 (HIV-1) group M strains (M-Vpu), those from the nonpandemic HIV-1 group O (O-Vpu) are not able to co...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Vigan, Raphaël, Neil, Stuart J. D.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2011
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3196455/
https://ncbi.nlm.nih.gov/pubmed/21775465
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00479-11
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