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Role of the Endocytic Pathway in the Counteraction of BST-2 by Human Lentiviral Pathogens

The interferon-inducible transmembrane protein BST-2 (CD317, tetherin) restricts the release of several enveloped viruses from infected cells. BST-2 is broadly active against retroviruses, including HIV-1 and HIV-2. To counteract this host defense, HIV-1 uses the accessory protein Vpu, whereas HIV-2...

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Detalhes bibliográficos
Main Authors: Lau, David, Kwan, Wilson, Guatelli, John
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3196438/
https://ncbi.nlm.nih.gov/pubmed/21813615
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02633-10
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