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Epstein-Barr Virus Nuclear Antigen 1 Replication and Segregation Functions in Nasopharyngeal Carcinoma Cell Lines

Nasopharyngeal carcinomas (NPC) are usually Epstein-Barr virus (EBV) positive, but, with the exception of C666-1 cells, these cells lose the EBV genomes when grown in culture. Maintenance of EBV requires the viral EBV nuclear antigen 1 (EBNA1) protein, which ensures the replication and mitotic segre...

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Autores principales: Sivachandran, Nirojini, Thawe, Natalia N., Frappier, Lori
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology 2011
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3196394/
https://ncbi.nlm.nih.gov/pubmed/21795327
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.05293-11
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