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Mechanisms Controlling Virulence Thresholds of Mixed Viral Populations
The propensity of RNA viruses to revert attenuating mutations contributes to disease and complicates vaccine development. Despite the presence of virulent revertant viruses in some live-attenuated vaccines, disease from vaccination is rare. This suggests that in mixed viral populations, attenuated v...
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Main Authors: | , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
American Society for Microbiology
2011
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3196390/ https://ncbi.nlm.nih.gov/pubmed/21795346 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00355-11 |
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