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Receptor-Mediated Activation of a Proinsulin-Transferrin Fusion Protein in Hepatoma Cells
A proinsulin-transferrin (ProINS-Tf) recombinant fusion protein was designed and characterized for the sustained release of an active form of insulin (INS) by hepatoma cells. During incubation with H4IIE hepatoma cells, a gradual decline of ProINS-Tf concentration, with a concomitant generation of t...
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| Asıl Yazarlar: | , , , |
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| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
2011
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| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3196267/ https://ncbi.nlm.nih.gov/pubmed/21756950 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jconrel.2011.06.029 |
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