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Fluorescence image screening for chemical compounds modifying cholesterol metabolism and distribution
An automated fluorescence microscopy assay using a nontoxic cholesterol binding protein, θ toxin domain 4, (D4), was developed in order to identify chemical compounds modifying intracellular cholesterol metabolism and distribution. Using this method, we screened a library of 1,056 compounds and iden...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The American Society for Biochemistry and Molecular Biology
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3196239/ https://ncbi.nlm.nih.gov/pubmed/21862703 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1194/jlr.D018184 |
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