Identification of Human Fumarylacetoacetate Hydrolase Domain-containing Protein 1 (FAHD1) as a Novel Mitochondrial Acylpyruvase

The human fumarylacetoacetate hydrolase (FAH) domain-containing protein 1 (FAHD1) is part of the FAH protein superfamily, but its enzymatic function is unknown. In the quest for a putative enzymatic function of FAHD1, we found that FAHD1 exhibits acylpyruvase activity, demonstrated by the hydrolysis...

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Bibliographic Details
Main Authors: Pircher, Haymo, Straganz, Grit D., Ehehalt, Daniela, Morrow, Geneviève, Tanguay, Robert M., Jansen-Dürr, Pidder
Format: Artigo
Language:Inglês
Published: American Society for Biochemistry and Molecular Biology 2011
Subjects:
Enzymology
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3196145/
https://ncbi.nlm.nih.gov/pubmed/21878618
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.264770
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