Transcriptional Regulation of Neural Retina Leucine Zipper (Nrl), a Photoreceptor Cell Fate Determinant

The transcription factor neural retina leucine zipper (Nrl) is a critical determinant of rod photoreceptor cell fate and a key regulator of rod differentiation. Nrl(−/−) rod precursors fail to turn on rod genes and instead differentiate as cones. Furthermore, NRL mutations in humans cause retinitis...

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Main Authors: Montana, Cynthia L., Lawrence, Karen A., Williams, Natecia L., Tran, Nicholas M., Peng, Guang-Hua, Chen, Shiming, Corbo, Joseph C.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Biochemistry and Molecular Biology 2011
Fag:
Gene Regulation
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3196091/
https://ncbi.nlm.nih.gov/pubmed/21865162
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.279026
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