Cdc42 Regulates Extracellular Matrix Remodeling in Three Dimensions

Extracellular matrix (ECM) actively participates in normal cell regulation and in the process of tumor progression. The Rho GTPase Cdc42 has been shown to regulate cell-ECM interaction in conventional two-dimensional culture conditions by using dominant mutants of Cdc42 in immortalized cell lines th...

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Bibliographic Details
Main Authors: Sipes, Nisha S., Feng, Yuxin, Guo, Fukun, Lee, Hyung-Ok, Chou, Fu-Sheng, Cheng, Jonathan, Mulloy, James, Zheng, Yi
Format: Artigo
Language:Inglês
Published: American Society for Biochemistry and Molecular Biology 2011
Subjects:
Cell Biology
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3196090/
https://ncbi.nlm.nih.gov/pubmed/21880728
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.283176
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