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Degradative inactivation of cyclic AMP-dependent protein kinase by a membranal proteinase is restricted to the free catalytic subunit in its native conformation.

A membranal proteinase from brush-border epithelial cells of the rat small intestine was shown to bring about a restricted and limited degradation of the free catalytic subunit (C) of cyclic AMP-dependent protein kinase (ATP:protein phosphotransferase, EC 2.7.1.37) with concomitant inactivation of t...

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Bibliografiske detaljer
Udgivet i:Proc Natl Acad Sci U S A
Principais autores: Alhanaty, E, Patinkin, J, Tauber-Finkelstein, M, Shaltiel, S
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 1981
Fag:
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC319595/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6267595/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.78.6.3492
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