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Computational modelling of 5-HT receptor-mediated reorganization of the brainstem respiratory network

Brainstem respiratory neurons express the glycine α(3) receptor (Glyα(3)R), which is a target of modulation by several serotonin (5-HT) receptor agonists. Application of the 5-HT(1A) receptor (5-HT(1A)R) agonist 8-OH-DPAT was shown (1) to depress cellular cAMP, leading to dephosphorylation of Glyα(3...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Shevtsova, Natalia A., Manzke, Till, Molkov, Yaroslav I., Bischoff, Anne, Smith, Jeffrey C., Rybak, Ilya A., Richter, Diethelm W.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2011
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3195875/
https://ncbi.nlm.nih.gov/pubmed/21899601
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1460-9568.2011.07825.x
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