Immunomodulatory effects induced by CTLA4-Ig with donor PBMC infusion in canine MHC-haploidentical nonmyeloablative hematopoietic cell transplantation

BACKGROUND: Previously, cytotoxic T lymphocyte antigen 4 (CTLA4)-Ig has been shown to allow sustained engraftment in dog leukocyte antigen (DLA)-identical hematopoietic cell transplant (HCT) after nonmyeloablative conditioning with 100 cGy total body irradiation (TBI). In the current study, we inves...

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Main Authors: Chen, Yun, Fukuda, Takahiro, Thakar, Monica S., Kornblit, Brian T., Storer, Barry E., Santos, Erlinda B., Storb, Rainer, Sandmaier, Brenda M.
Format: Artigo
Sprog:Inglês
Udgivet: 2011
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3195840/
https://ncbi.nlm.nih.gov/pubmed/21846291
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3109/14653249.2011.586997
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