The risk of coronary thrombosis with cyclo-oxygenase-2 inhibitors does not vary with polymorphisms in two regions of the cyclo-oxygenase-2 gene

AIMS: To investigate whether polymorphisms of the cyclo-oxygenase-2 (COX-2) gene modify the adverse cardiovascular effects of COX-2 inhibitors. METHODS: A case control study was conducted in the Hunter Region of New South Wales, Australia. Cases (n = 460) were hospitalized with acute coronary syndro...

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Autori principali: McGettigan, Patricia, Lincz, Lisa F, Attia, John, McElduff, Patrick, Bissett, Linda, Peel, Roseanne, Stokes, Barrie, Hancock, Stephen, Henderson, Kim, Seldon, Michael, Henry, David
Natura: Artigo
Lingua:Inglês
Pubblicazione: Blackwell Science Inc 2011
Soggetti:
Haemostasis Themed Issue
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3195745/
https://ncbi.nlm.nih.gov/pubmed/21371074
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2125.2011.03957.x
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