Pigment Epithelium-derived Factor (PEDF) Promotes Tumor Cell Death by Inducing Macrophage Membrane Tumor Necrosis Factor-related Apoptosis-inducing Ligand (TRAIL)

Pigment epithelium-derived factor (PEDF) is an intrinsic anti-angiogenic factor and a potential anti-tumor agent. The tumoricidal mechanism of PEDF, however, has not been fully elucidated. Here we report that PEDF induces the apoptosis of TC-1 and SK-Hep-1 tumor cells when they are cocultured with b...

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Detalhes bibliográficos
Main Authors: Ho, Tsung-Chuan, Chen, Show-Li, Shih, Shou-Chuan, Chang, Shing-Jyh, Yang, Su-Lin, Hsieh, Jui-Wen, Cheng, Huey-Chuan, Chen, Lee-Jen, Tsao, Yeou-Ping
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2011
Assuntos:
Immunology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3195575/
https://ncbi.nlm.nih.gov/pubmed/21846721
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.266064
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