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Vav Protein Guanine Nucleotide Exchange Factor Regulates CD36 Protein-mediated Macrophage Foam Cell Formation via Calcium and Dynamin-dependent Processes

Atherosclerosis, a chronic inflammatory disease, results in part from the accumulation of modified lipoproteins in the arterial wall and formation of lipid-laden macrophages, known as “foam cells.” Recently, we reported that CD36, a scavenger receptor, contributes to activation of Vav-family guanine...

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Detalles Bibliográficos
Main Authors: Rahaman, S. Ohidar, Zhou, Gang, Silverstein, Roy L.
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Biochemistry and Molecular Biology 2011
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3195569/
https://ncbi.nlm.nih.gov/pubmed/21865158
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.265082
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